Detalles de la búsqueda
1.
Epigallocatechin gallate is a potent inhibitor of cystathionine beta-synthase: Structure-activity relationship and mechanism of action.
Nitric Oxide;
128: 12-24, 2022 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35973674
2.
Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors.
Molecules;
25(16)2020 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-32824311
3.
Indirubin Analogues Inhibit Trypanosoma brucei Glycogen Synthase Kinase 3 Short and T. brucei Growth.
Antimicrob Agents Chemother;
63(6)2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30910902
4.
NmeA, a novel efflux transporter specific for nucleobases and nucleosides, contributes to metal resistance in Aspergillus nidulans.
Mol Microbiol;
105(3): 426-439, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28509393
5.
Exploring and exploiting the systemic effects of deregulated replication licensing.
Semin Cancer Biol;
37-38: 3-15, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26707000
6.
Synthesis, Docking Study and Kinase Inhibitory Activity of a Number of New Substituted Pyrazolo[3,4-c]pyridines.
Chem Pharm Bull (Tokyo);
65(1): 66-81, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28049917
7.
Combined Virtual and Experimental Screening for CK1 Inhibitors Identifies a Modulator of p53 and Reveals Important Aspects of in Silico Screening Performance.
Int J Mol Sci;
18(10)2017 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28984824
8.
Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine ß-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer.
Pharmacol Res;
113(Pt A): 18-37, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27521834
9.
Discovery of the glycogen phosphorylase-modulating activity of a resveratrol glucoside by using a virtual screening protocol optimized for solvation effects.
Planta Med;
81(6): 507-16, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25875507
10.
Erratum to 'Exploring and exploiting the systemic effects of deregulated replication licensing' [Seminars in Cancer Biology 37-38C, (2016) 3-15].
Semin Cancer Biol;
43: 180, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28254408
11.
Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 transporter.
J Biol Chem;
287(44): 36792-803, 2012 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22969088
12.
A substrate translocation trajectory in a cytoplasm-facing topological model of the monocarboxylate/H⺠symporter Jen1p.
Mol Microbiol;
81(3): 805-17, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21651629
13.
Cockayne Syndrome Group B (CSB): The Regulatory Framework Governing the Multifunctional Protein and Its Plausible Role in Cancer.
Cells;
10(4)2021 04 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33920220
14.
Novel Aryl-Substituted Pyrimidones as Inhibitors of 3-Mercaptopyruvate Sulfurtransferase with Antiproliferative Efficacy in Colon Cancer.
J Med Chem;
64(9): 6221-6240, 2021 05 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33856792
15.
Two new peltogynoids from Acacia nilotica Delile with kinase inhibitory activity.
Planta Med;
76(5): 458-60, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19844867
16.
Lipophilic Guanylhydrazone Analogues as Promising Trypanocidal Agents: An Extended SAR Study.
Curr Pharm Des;
26(8): 838-866, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32039675
17.
From bench to bedside, via desktop. Recent advances in the application of cutting-edge in silico tools in the research of drugs targeting bromodomain modules.
Biochem Pharmacol;
159: 40-51, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30414936
18.
Immunohisto(cyto)chemistry: an old time classic tool driving modern oncological therapies.
Histol Histopathol;
34(4): 335-352, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-30480312
19.
Design, synthesis and biological evaluation of novel substituted purine isosters as EGFR kinase inhibitors, with promising pharmacokinetic profile and in vivo efficacy.
Eur J Med Chem;
176: 393-409, 2019 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31125894
20.
Senescence and senotherapeutics: a new field in cancer therapy.
Pharmacol Ther;
193: 31-49, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30121319